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Megagrisevit Mono (Clostebol) is basically testosterone with an added 4-chloro group in the A-ring. What does that mean? All it means is that it cannot properly interact with the 5-Alpha-Reductase enzyme to be 5-alpha reduced to dihydrotestosterone. Thus, hair loss and acne caused by DHT is not possible. Aromatization is also not possible, so estrogenic side effects aren't likely either. On paper Megagrisevit Mono looks great and it basically has a similar anabolic: androgenic ratio to other steroids like Masteron. But I have to say that since it isn't DHT-Derived like Masteron is, it's probably not going to have some of the cool precontest physique hardening properties of Masteron and other similar compounds. To be perfectly frank, Clostebol is just a pretty weak testosterone-derived steroid. I wish I could say that it has more to offer, but really, it doesnt. Megagrisevit Mono (the brand name for Clostebol Acetate) is presented in a 10 ml per 1.5 ml vial. This means you'll need to fill up on many oily injections, which you are going to have problems finding injection sites for. You know what else? The short ester found on this stuff will mean that you have to basically load up on tons of this stuff at least every other day. Women may be able to get by with a bit less, possibly 1.5mls every other day. There is an oral form of clostebol acetate that is under the same name of Megagrisevit Mono, but I can't see that form being extremely effective either. I think you'll need to take 100-200mgs of it daily. Remember, it isn't 17-alpha-alkylated, so it'll be destroyed by your liver in pretty short order. I've heard many reports on Steroid.com that a few people have had access to this drug and liked it, but I've not been able to confirm this with anyone reputable. My advice is that this drug has been discontinued for a good reason and should be avoided by most serious athletes and bodybuilders.
As a side note, I'm not really too thrilled with the addition of an Acetate ester to improve oral absorption. When we look at Trenbolone Acetate (oral) vs./ Trenbolone Acetate (Injectable), on the chart below, we can see that the injectable is around 100 xs as effective for increasing Labc weight, which can be fairly accurately used as a measure of anabolism:
(SC= injection; oral = oral)
One of the most interesting things I found when researching this compound is that an athlete had tested positive for it by having sex with a woman who had used a Brazilian compound known as Trofodermin, which is produced by Searle. This product is indicated for cervicitis, postoperative vaginitis, and ulcerative vaginitis, and the recommended dose is 5g 1-2x a day. And, of course, it is to be administered intravaginally. As a result, the athlete who tested positive for Clostebol claimed to have had sex with a woman who had been using this product. Then tests (all in the name of science) were performed where two couples had intercourse following the vaginal application of Trofodermin, and the men were tested via urinalysis for Clostebol (before and after intercourse). It was then determined that Clostebol can indeed be absorbed through the penis following vaginal administration of a Clostebol containing compound. Whoever said that anti-doping research is no fun?
Well, in any case, the subjects involved had fun, although I suppose they weren't Olympic athletes. I suppose it would suck to be in the control group for that study, huh?
Anyway, here's how your body metabolizes Clostebol:
Megagrisevit Mono Profile
(Clostebol Acetate)
[4-chloro-androst-4-en-3-one, 17b-ol]
Molecular Formula: C21 H29Cl O3
Molecular Weight): 322.8741
Melting Point: N/A
Manufacturer: N/A
Effective Dose: (injectable) 100mgs/day, (oral) 100-200mgs/day
Active Life: (injectable) 2-3 days, (oral) 4-6 hours
Detection Time: 3 months
Anabolic/Androgenic Ratio: 46:25
References:
1. Clinical Chemistry. 2004;50:456-457. 2004 American Association for Clinical Chemistry, Inc.
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